Brain Morphology and Function Report

Name	Superior longitudinal fasciculus
Brain Morphology	The superior longitudinal fasciculus (also called the superior longitudinal fascicle or SLF) is a pair of long bi-directional bundles of neurons connecting the front and the back of the cerebrum. Each association fiber bundle is lateral to the centrum ovale of a cerebral hemisphere and connects the frontal, occipital, parietal, and temporal lobes. The neurons pass from the frontal lobe through the operculum to the posterior end of the lateral sulcus where numerous neurons radiate into the occipital lobe and other neurons turn downward and forward around the putamen and radiate to anterior portions of the temporal lobe.
No. of Studies (Positive/Negative)	3(3/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
superior longitudinal fasciculus	Zou, 2008	patients and normal controls		We found a significant decrease in fractional anisotropy (FA...... We found a significant decrease in fractional anisotropy (FA) in the left hemisphere, including the anterior limb of the internal capsule and the inferior parietal portion of the superior longitudinal fasciculus, in patients with MDD compared with healthy controls. More...
superior longitudinal fasciculus (SLF)	Matthews, 2011	patients and normal controls		MDD relative to non-MDD individuals showed lower fractional ...... MDD relative to non-MDD individuals showed lower fractional anisotropy (FA) in several white matter tracts including the superior longitudinal fasciculus (SLF). More...
superior longitudinal fasciculi	Huang, 2011	high-risk people and normal controls		Adolescents at high risk for unipolar depression had lower f...... Adolescents at high risk for unipolar depression had lower fractional anisotropy (FA) values in the left cingulum, splenium of the corpus callosum, superior longitudinal fasciculi, uncinate, and inferior fronto-occipital fasciculi than did controls. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
superior longitudinal fasciculus (SLF)		Depressed mood(depressive mood)	symptoms	Matthews, 2011	patients and normal controls		Greater depressive symptom severity correlated negatively wi...... Greater depressive symptom severity correlated negatively with FA (fractional anisotropy) in the SLF. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web