Brain Morphology and Function Report

Name	Sensory cortex
Brain Morphology	The sensory cortex can refer informally to the primary somatosensory cortex, or it can be used as an umbrella term for the primary and secondary cortices of the different senses (two cortices each, on left and right hemisphere): the visual cortex on the occipital lobes, the auditory cortex on the temporal lobes, the primary olfactory cortex on the uncus of the piriform region of the temporal lobes, the gustatory cortex on the insular lobe (also referred to as the insular cortex), and the primary somatosensory cortex on the anterior parietal lobes. Just posterior to the primary somatosensory cortex lies the somatosensory association cortex, which integrates sensory information from the primary somatosensory cortex (temperature, pressure, etc.) to construct an understanding of the object being felt. Inferior to the frontal lobes are found the olfactory bulbs, which receive sensory input from the olfactory nerves and route those signals throughout the brain. Not all olfactory information is routed to the olfactory cortex. Some neural fibers are routed directly to limbic structures, while others are routed to the supraorbital region of the frontal lobe. Such a direct limbic connection makes the olfactory sense unique.
No. of Studies (Positive/Negative)	4(3/1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
left premotor cortices	Nofzinger, 2004	patients and normal controls		depressed patients showed greater activation in left premoto...... depressed patients showed greater activation in left premotor cortices More...
primary sensorimotor cortices	Nofzinger, 2004	patients and normal controls		depressed patients showed greater activation in primary sens...... depressed patients showed greater activation in primary sensorimotor cortices More...
right pre-supplementary motor area	Cheng, 2010	patients and normal controls		the regional GMV(grey matter volume) of the right pre-supple...... the regional GMV(grey matter volume) of the right pre-supplementary motor area (pre-SMA) was smaller in MDD patients More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
somato-sensory cortex		ATP-citrate synthase(citrate synthase)	protein	Gardner, 2008	patients only		Voxel-based analysis showed significantly higher 99mTc-HMPAO...... Voxel-based analysis showed significantly higher 99mTc-HMPAO retention in the patients with low CS (citrate synthase) compared with the patients with normal CS in the posterior and inferior frontal cortex, the superior and posterior temporal cortex, the somato-sensory cortex, and the associative parietal cortex. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description
somatosensory cortices		Depressed mood(depression)	symptoms	Giesecke, 2005	patients and normal controls		Neither the level of symptoms of depression nor the presence...... Neither the level of symptoms of depression nor the presence of comorbid MDD was associated with the results of sensory testing or the magnitude of neuronal activation in brain areas associated with the sensory dimension of pain (primary and secondary somatosensory cortices). More...