MK4MDD

Gene Report

Basic Information
Approved Symbol SIRT2
Approved Name sirtuin 2
Previous Symbol SIR2L
Previous Name "sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 2", "sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)"
Location 19q13
Position chr19:39390162-39390463 (-)
External Links Entrez Gene: 22933
Ensembl: ENSG00000068903
UCSC: uc002ojt.2
HGNC ID: 10886
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between SIRT2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
sirtuin Abe, 2011 patients and normal controls The SIRT1, 2 and 6 mRNA levels in MDD patients decreased sig...... The SIRT1, 2 and 6 mRNA levels in MDD patients decreased significantly in those who were in a depressive state compared to healthy controls More...

Positive relationships between SIRT2 and other components at different levels (count: 0) Help
Positive relationship network of SIRT2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SIRT2 and MDD (count: 0)
Negative relationships between SIRT2 and other components at different levels (count: 0) Help
SIRT2 related SNPs in MK4MDD (count: 0)
SIRT2 related proteins in MK4MDD (count: 0)
SIRT2 related GO terms (count: 103)
SIRT2 related KEGG pathways (count: 0)
SIRT2 related BioCarta pathways (count: 0)
SIRT2 related Reactome pathways (count: 0)
SIRT2 related interactors from protein-protein interaction data in HPRD (count: 7)