MK4MDD

Signs Report

Basic Information
Name Retinal contrast gain
Description "To assess a possible relationship between visual contrast processing at the level of the retina and depressive phenomena, we measured the pattern electroretinogram (PERG)-based contrast gain (hereafter ""contrast gain"") to achromatic, gray checkerboard stimuli in healthy control subjects, unmedicated patients with MDD, and medicated patients with MDD. The PERG is an objective electrophysiologic response, recorded at the cornea in response to visual pattern stimulation. It mainly represents activity of the retinal ganglion cells and thus can serve as a surrogate marker of retinal information processing from the photoreceptors to the beginning of the optic nerve. (E. Bubl et al.,2010; PMID: 20359698)"
No. of Studies (Positive/Negative) 1 (1/0) Help

Positive relationship between Retinal contrast gain and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
retinal contrast gain Bubl, 2010 patients and normal controls Unmedicated and medicated depressed patients displayed drama...... Unmedicated and medicated depressed patients displayed dramatically lower retinal contrast gain. We found a strong and significant correlation between contrast gain and severity of depression. More...

Positive relationships between Retinal contrast gain and other components at different levels (count: 0) Help
Positive relationship network of Retinal contrast gain in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Retinal contrast gain and MDD (count: 0)
Negative relationships between Retinal contrast gain and other components at different levels (count: 0) Help