Brain Morphology and Function Report

Name	Pituitary gland
Brain Morphology	In vertebrate anatomy the pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing 0.5 g (0.02 oz.), in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain, and rests in a small, bony cavity (sella turcica) covered by a dural fold (diaphragma sellae).
Brain Function	The pituitary is functionally connected to the hypothalamus by the median eminence via a small tube called the infundibular stem (Pituitary Stalk). The pituitary fossa, in which the pituitary gland sits, is situated in the sphenoid bone in the middle cranial fossa at the base of the brain. The pituitary gland secretes nine hormones that regulate homeostasis.
Picture	From Wiki.
No. of Studies (Positive/Negative)	3(3/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
pituitary gland	MacMaster, 2006	patients and normal controls	larger pituitary gland volume (19%)	The MDD boys had larger pituitary gland volume (19%) compare...... The MDD boys had larger pituitary gland volume (19%) compared with male control subjects. More...
pituitary gland	MacMaster, 2004	patients and normal controls	F=6.43, df=1, 29, P-value = 0.02; MDD subjects demonstrated a 25% increase in pituitary gland volume	ANCOVA covarying for age, sex and intracranial volume (ICV) ...... ANCOVA covarying for age, sex and intracranial volume (ICV) revealed a significant difference between the two groups (F=6.43, df=1, 29, P=0.02; MDD subjects demonstrated a 25% increase in pituitary gland volume). More...
pituitary gland volume	MacMaster, 2004	patients and normal controls	25% increase	MDD subjects demonstrated a 25% increase in pituitary gland ...... MDD subjects demonstrated a 25% increase in pituitary gland volume. More...
pituitary gland	MacMaster, 2008	patients and normal controls	P-value = 0.049	Post hoc analysis revealed that controls had a significantly...... Post hoc analysis revealed that controls had a significantly smaller pituitary gland volume than both bipolar patients (p = 0.019) and depressed patients (p = 0.049). More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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