Brain Morphology and Function Report

Name	Motor cortex
Brain Morphology	The motor cortex can be divided into four main parts: 1. the primary motor cortex (or M1), responsible for generating the neural impulses controlling execution of movement; 2. the secondary motor cortices, including the posterior parietal cortex, responsible for transforming visual information into motor commands; 3. the premotor cortex, responsible for motor guidance of movement and control of proximal and trunk muscles of the body; 4. the supplementary motor area (or SMA), responsible for planning and coordination of complex movements such as those requiring two hands. Other brain regions outside the cortex are also of great importance to motor function, most notably the cerebellum and subcortical motor nuclei.
Brain Function	Motor cortex is a term that describes regions of the cerebral cortex involved in the planning, control, and execution of voluntary motor functions.
Picture	From Wiki.
No. of Studies (Positive/Negative)	5(5/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
left motor areas	Frodl, 2010	patients and normal controls		In contrast, functional connectivity between the OFC and the...... In contrast, functional connectivity between the OFC and the right dorsolateral prefrontal cortex (DLPFC), right inferior frontal operculum, and left motor areas was increased in patients compared with healthy control subjects. More...
supplementary motor cortex	Smoski, 2011	patients and normal controls		The MDD group showed lower activation than controls when ant...... The MDD group showed lower activation than controls when anticipating pleasant image rewards in supplementary motor cortex. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
left motor areas		Orbitofrontal cortex(orbitofrontal cortex)	brain morphology and function	Frodl, 2010	patients and normal controls		In contrast, functional connectivity between the OFC and the...... In contrast, functional connectivity between the OFC and the right dorsolateral prefrontal cortex (DLPFC), right inferior frontal operculum, and left motor areas was increased in patients compared with healthy control subjects. More...
left motor areas		Orbitofrontal cortex(orbitofrontal cortex (OFC))	brain morphology and function	Frodl, 2010	patients and normal controls		Functional connectivity between the OFC and the left motor a...... Functional connectivity between the OFC and the left motor areas was increased in patients compared with healthy control subjects. More...
supplementary motor area		Orbitofrontal cortex(orbitofrontal volumes)	brain morphology and function	Scheuerecker, 2010	patients and normal controls		Within this cerebral network, the orbitofrontal volumes were...... Within this cerebral network, the orbitofrontal volumes were negatively correlated in depressed patients but not in healthy controls with changes in blood oxygen level-dependent signal in the middle frontal gyrus, caudate nucleus, precuneus and supplementary motor area. More...
left supplemental motor area		Psychomotor performance(motor control)	cognition and behavior	Walther, 2012	patients and normal controls		MDD patients had reduced activity level (AL). Groups differe...... MDD patients had reduced activity level (AL). Groups differed in four clusters associated with motor control. MDD patients had positive associations in the right orbitofrontal cortex and inverse associations in the left supplemental motor area. More...
supplementary motor area		Depressed mood(melancholic features)	symptoms	Exner, 2009	patients and normal controls		Regional volumes of the right pre-SMA (supplementary motor a...... Regional volumes of the right pre-SMA (supplementary motor area) were reduced in depressive subjects with melancholic features. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web