Gene Report

Basic Information

Approved Symbol	MAGEL2
Approved Name	MAGE-like 2
Previous Symbol	NDNL1
Symbol Alias	nM15
Location	15q11-q12
Position	chr15:23892890-23892988 (-)
External Links	Entrez Gene: 54551 Ensembl: ENSG00000254585 UCSC: uc001ywj.4 HGNC ID: 6814
No. of Studies (Positive/Negative)	1(0/1)
Type	Literature-origin

Positive relationships between MAGEL2 and MDD (count: 0)

Positive relationships between MAGEL2 and other components at different levels (count: 0)

Positive relationship network of MAGEL2 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between MAGEL2 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
MAGEL2	Fukuo Y, 2010	patients and nomal controls		We did not find any association between MAGEL2 and schizophr...... We did not find any association between MAGEL2 and schizophrenia, BP or MDD in allele/genotype-wise analysis or haplotype-wise analysis. More...

Negative relationships between MAGEL2 and other components at different levels (count: 0)

MAGEL2 related SNPs in MK4MDD (count: 0)

MAGEL2 related proteins in MK4MDD (count: 0)

MAGEL2 related GO terms (count: 14)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0030904	retromer complex	cellular component	IDA[23452853]
GO:0042752	regulation of circadian rhythm	biological process	ISS
GO:0070534	protein K63-linked ubiquitination	biological process	IMP[23452853]
GO:0005769	early endosome	cellular component	IEA
GO:0006351	transcription, DNA-templated	biological process	IEA
GO:0005515	protein binding	molecular function	IPI[23452853]
GO:0045892	negative regulation of transcription, DNA-templated	biological process	ISS
GO:0034314	Arp2/3 complex-mediated actin nucleation	biological process	IDA[23452853]
GO:0042147	retrograde transport, endosome to Golgi	biological process	IDA[23452853]
GO:0004842	ubiquitin-protein transferase activity	molecular function	IMP[23452853]
GO:0051127	positive regulation of actin nucleation	biological process	IEA
GO:0005768	endosome	cellular component	IDA[23452853]
GO:0005634	nucleus	cellular component	ISS
GO:0048511	rhythmic process	biological process	IEA

MAGEL2 related KEGG pathways (count: 0)

MAGEL2 related BioCarta pathways (count: 0)

MAGEL2 related Reactome pathways (count: 0)

MAGEL2 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms