Cell Report

Name	Lymphocytes
Description	White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.
No. of Studies (Positive/Negative)	6(6/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
lymphocyte	Targum, 1989	patients and normal controls	P-value-value<0.01	Depressed women revealed significantly reduced absolute lymp...... Depressed women revealed significantly reduced absolute lymphocytes (p less than 0.01), T cells (p less than 0.01), and T helper cells (p less than 0.02) compared to normal elderly women. More...
Lymphocyte	Schleifer, 1984	patients and normal controls		Lymphocyte stimulation by phytohemagglutinin, concanavalin A...... Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. More...
Lymphocyte	Lima, 2002	patients and normal controls		Lymphocytes serotonin transporter number was significantly r...... Lymphocytes serotonin transporter number was significantly reduced, while the affinity was unchanged, in patients with major depression disorder as compare to controls. More...
lymphocyte	Fajardo, 2003	patients and normal controls		There was a reduction in serotonin turnover rate indicated b...... There was a reduction in serotonin turnover rate indicated by an increase in the ratio serotonin/5-hydroxyindoleacetic acid, but not in that of dopamine, in lymphocytes of major depression patients. More...
lymphocytes	Mizrahi, 2004	patients and normal controls		The basal concentration of cAMP was 50% lower in mononuclear...... The basal concentration of cAMP was 50% lower in mononuclear cells and lymphocytes from the depressed patients compared with the control subjects. The response to forskolin was significantly smaller in lymphocytes of major depression patients than in the controls, but no difference was evident in the mononuclear cell preparations. There was a significant increase in cAMP produced by 5HT in mononuclear cells from the control group, but not in their lymphocytes. More...
lymphocyte	Gonzalez, 2007	patients and normal controls		Basal proliferation was three times higher in depressed pati...... Basal proliferation was three times higher in depressed patients than in controls More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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