Cell Report

Name	Leukocytes
Description	White blood cells. These include granular leukocytes ( BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes ( LYMPHOCYTES and MONOCYTES).
No. of Studies (Positive/Negative)	5(5/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
leukocyte	Schleifer, 1996	patients and normal controls		Young adult subjects with major depression had more circulat...... Young adult subjects with major depression had more circulating leukocytes and granulocytes, fewer CD56+ (natural killer [NK]) cells, and, when the number of circulating NK cells was controlled, less NK cell activity. More...
leucocyte	Seidel, 1996	patients and normal controls		We detected significant increases in the numbers of leucocyt...... We detected significant increases in the numbers of leucocytes, granulocytes, platelets and monocytes in the depressed patients More...
leukocytes	Numata, 2009	patients and normal controls	P-value-value<0.0001	In the leukocytes, a significantly higher expression of the ...... In the leukocytes, a significantly higher expression of the PDE4B mRNA was observed in the drug-naive MDD patients compared with control subjects (P < 0.0001) and the expression of the MDD patients significantly decreased after antidepressant treatment (P = 0.030). I More...
white cell	Boettger, 2010	patients and normal controls		Patients showed increased white cell counts before and after...... Patients showed increased white cell counts before and after exercise. More...
neutrophils	Ren, 2011	patients and normal controls		We found that the CRE-DNA binding activity and CREB protein ...... We found that the CRE-DNA binding activity and CREB protein expression were significantly decreased in the neutrophils of drug-free MDD patients compared with normal control subjects. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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