Neurobiological Component Report

Name	Late positive component
Description	The LPC (Late Positive Component or Late Positive Complex) is a positive-going event-related brain potential (ERP) component that has been important in studies of explicit recognition memory. It is generally found to be largest over parietal scalp sites (relative to reference electrodes placed on the mastoid processes), beginning around 400-500 ms after the onset of a stimulus and lasting for a few hundred milliseconds.
No. of Studies (Positive/Negative)	9 (9/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
late positive component	Pelosi, 2000	patients and normal controls		In the 375-840 ms epoch, the patients' responses showed larg...... In the 375-840 ms epoch, the patients' responses showed large amplitude sustained negative activity, maximal at Cz and a reduced late positive wave. More...
late positive component	Deveney, 2004	patients and normal controls		Individuals with MDD exhibited equivalent SW amplitudes for ...... Individuals with MDD exhibited equivalent SW amplitudes for positive and negative facial stimuli. More...
late positive component	Shestyuk, 2005	patients and normal controls		Compared with control individuals, MDD participants exhibite...... Compared with control individuals, MDD participants exhibited decreased brain responses to positive relative to negative or neutral stimuli. This decrease in brain activity during processing of positive information was evident across all sites and SW components. More...
late positive component	Pause, 2003	patients and normal controls		At the beginning of the therapy, visual stimulus processing ...... At the beginning of the therapy, visual stimulus processing was attenuated in depressive subjects at a relatively late processing level (reduced amplitudes of the P3 and pSW in response to colors and emotional slides). More...
late positive component	Perez-Edgar, 2006	high-risk people and normal controls		Children of parents with COD (childhood-onset depression) sh...... Children of parents with COD (childhood-onset depression) showed larger P3 and slow wave amplitudes in anterior scalp sites, particularly during the affective Posner task. More...
LPC	Iakimova, 2009	patients and normal controls		Patients exhibited prolonged latency of the LPC in semantic ...... Patients exhibited prolonged latency of the LPC in semantic judgment More...
late positive component	Shestyuk, 2010	patients and normal controls		Greater component amplitudes in response to negative relativ...... Greater component amplitudes in response to negative relative to positive self-referent items were evident in individuals with current depression during effortful encoding (indexed by the late positive component). More...
late positive component (LPC)	Yao, 2010	patients and normal controls		The patients showed shorter LPC latency in response to negat...... The patients showed shorter LPC latency in response to negative experimental targets, whereas the controls showed delayed LPC latency in response to negative experimental targets. More...
late positive potential	Foti, 2010	patients and normal controls		The late positive potential was also increased in response t...... The late positive potential was also increased in response to threatening faces, but only among never-depressed individuals. In the MDD group, this electrocortical response to emotional faces was absent. More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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