MK4MDD

Protein Report

Basic Information
Protein Name Interleukin-2 receptor subunit alpha
UniPortKB P01589
No. of Studies (Positive/Negative) 2 (2/0) Help
Type Literature-origin
Positive relationship between Interleukin-2 receptor subunit alpha and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
interleukin-2 receptor Wichers, 2006 high-risk people Baseline soluble interleukin-2 receptor (sIL-2r), interleuki...... Baseline soluble interleukin-2 receptor (sIL-2r), interleukin-6 (IL-6), and interleukin-10 (IL-10) concentrations were significantly increased in the five subjects that developed MDD during treatment compared with those that did not, with standardized effect sizes of 1.08, 1.16, and 1.25, respectively, controlling for marijuana use, cigarette smoking, and baseline level of depressive symptoms. More...
soluble interleukin-2 receptor (sIL-2R) Eller, 2009 patients and normal controls The results showed that the level of sIL-2R (soluble interle...... The results showed that the level of sIL-2R (soluble interleukin-2 receptor) was significantly lower in depressed patients in remission phase compared to the healthy controls and subjects with recurrent depression. Drug-nalve patients with major depressive disorder with recurrent episode had higher levels of sIL-2R than previously treated or patients with the first episode. More...

Positive relationships between Interleukin-2 receptor subunit alpha and other components at different levels (count: 2) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment

Positive relationship network of Interleukin-2 receptor subunit alpha in MK4MDD
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network_footer.jsp Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Interleukin-2 receptor subunit alpha and MDD (count: 0)
Negative relationships between Interleukin-2 receptor subunit alpha and other components at different levels (count: 0) Help
Related Gene Info
Gene Symbol Gene Name Type No. of Studies (Positive/Negative) Add to Relationship Set
IL2RA interleukin 2 receptor, alpha Protein mapped 0 (0/0)