MK4MDD

Molecule Report

Basic Information
Name Glycerophospholipids
Description Derivatives of phosphatidic acid in which the hydrophobic regions are composed of two fatty acids and a polar alcohol is joined to the C-3 position of glycerol through a phosphodiester bond. They are named according to their polar head groups, such as phosphatidylcholine and phosphatidylethanolamine.
MeSH ID D020404
No. of Studies (Positive/Negative) 2(2/0) Help

Positive relationship between Glycerophospholipids and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
glycerophosphocholine Caetano, 2005 patients and normal controls Depressed subjects had significantly lower levels of glycero...... Depressed subjects had significantly lower levels of glycerophosphocholine plus phosphocholine (GPC + PC; or choline-containing compounds) and higher myo-inositol levels in the left DLPFC compared to healthy controls. I More...
glycerophosphocholine Olvera, 2010 patients and normal controls MDD subjects also had significantly lower levels of GPC+PC i...... MDD subjects also had significantly lower levels of GPC+PC in the right AC than control subjects. More...

Positive relationships between Glycerophospholipids and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Glycerophospholipids in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between Glycerophospholipids and MDD (count: 0)
Negative relationships between Glycerophospholipids and other components at different levels (count: 0) Help