Gene Report

Basic Information

Approved Symbol	GPM6A
Approved Name	glycoprotein M6A
Previous Symbol	GPM6
Location	4q34
Position	chr4:176923742-176923842 (-)
External Links	Entrez Gene: 2823 Ensembl: ENSG00000150625 UCSC: uc003iug.4 HGNC ID: 4460
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between GPM6A and MDD (count: 0)

Positive relationships between GPM6A and other components at different levels (count: 1)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Name in Literature	Related Components
Gpm6a		Histone-lysine N-methyltransferase SETDB1(Setdb1 (Set domain, bifurcated 1))	protein	Jiang Y, 2010	animal model		Gene was occupied by Setdb1 in neuron Gene was occupied by Setdb1 in neuron

Positive relationship network of GPM6A in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between GPM6A and MDD (count: 0)

Negative relationships between GPM6A and other components at different levels (count: 0)

GPM6A related SNPs in MK4MDD (count: 0)

GPM6A related proteins in MK4MDD (count: 0)

GPM6A related GO terms (count: 18)

ID	Name	Type	Evidence
Literature-origin GO terms
GO:0043197	dendritic spine	cellular component	IEA

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0043025	neuronal cell body	cellular component	ISS
GO:0005262	calcium channel activity	molecular function	IEA
GO:0051491	positive regulation of filopodium assembly	biological process	ISS
GO:0044295	axonal growth cone	cellular component	ISS
GO:0016021	integral component of membrane	cellular component	IEA
GO:0001764	neuron migration	biological process	IDA[19298174]
GO:0007416	synapse assembly	biological process	ISS
GO:0070588	calcium ion transmembrane transport	biological process	IEA
GO:0003407	neural retina development	biological process	ISS
GO:0043005	neuron projection	cellular component	ISS
GO:0005515	protein binding	molecular function	IPI[24705354]
GO:0070062	extracellular exosome	cellular component	IDA[19056867]
GO:0005886	plasma membrane	cellular component	ISS
GO:0048863	stem cell differentiation	biological process	IDA[19298174]
GO:1903561	extracellular vesicle	cellular component	IDA[24769233]
GO:0048812	neuron projection morphogenesis	biological process	ISS
GO:0030175	filopodium	cellular component	ISS

GPM6A related KEGG pathways (count: 0)

GPM6A related BioCarta pathways (count: 0)

GPM6A related Reactome pathways (count: 0)

GPM6A related interactors from protein-protein interaction data in HPRD (count: 1)

Gene Report

Literature-origin GO terms

Gene mapped GO terms