MK4MDD

Brain Morphology and Function Report

Basic Information
Name Functional connectivity
Brain Morphology "Functional connectivity, which is defined as the temporal correlation between spatially remote neurophysiological events, is believed to serve as the mechanism for the coordination (or discoordination) of activity between different neural systems (dynamic cell assemblies across the cortex)(PMID:16779797). The brain functional connectivity is a collection of brain structures and networks which are involved in different cognitive functions (attention, adaptive control, emotional regulation, episodic memory, self-reflection, et al) . "
Brain Function The alteration in brain functional connectivity therefore might serve as a contributing factor to the disorganization syndrome (which has long been deemed a condition of impaired cognitive association) in many psychiatric and brain diseases (PMID:16779797).
No. of Studies (Positive/Negative) 2(2/0) Help

Positive relationships between Functional connectivity and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
long functional connections Fingelkurts, 2007 patients and normal controls In depressive patients the number and strength of long funct...... In depressive patients the number and strength of long functional connections were significantly larger for the right than for the left hemisphere. More...
short cortex functional connections Fingelkurts, 2007 patients and normal controls In depressive patients the number and strength of short cort...... In depressive patients the number and strength of short cortex functional connections were significantly larger for the left than for the right hemisphere More...
functional connectivity (FC) Zhou, 2010 patients and normal controls All of the altered FCs (functional connectivities) associate...... All of the altered FCs (functional connectivities) associated with the component regions increased in MDD. More...

Positive relationships between Functional connectivity and other components at different levels (count: 12) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Functional connectivity in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Functional connectivity and MDD (count: 0)
Negative relationships between Functional connectivity and other components at different levels (count: 0) Help