Brain Morphology and Function Report

Name	Functional connectivity
Brain Morphology	Functional connectivity, which is defined as the temporal correlation between spatially remote neurophysiological events, is believed to serve as the mechanism for the coordination (or discoordination) of activity between different neural systems (dynamic cell assemblies across the cortex)(PMID:16779797). The brain functional connectivity is a collection of brain structures and networks which are involved in different cognitive functions (attention, adaptive control, emotional regulation, episodic memory, self-reflection, et al) .
Brain Function	The alteration in brain functional connectivity therefore might serve as a contributing factor to the disorganization syndrome (which has long been deemed a condition of impaired cognitive association) in many psychiatric and brain diseases (PMID:16779797).
No. of Studies (Positive/Negative)	2(2/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
long functional connections	Fingelkurts, 2007	patients and normal controls		In depressive patients the number and strength of long funct...... In depressive patients the number and strength of long functional connections were significantly larger for the right than for the left hemisphere. More...
short cortex functional connections	Fingelkurts, 2007	patients and normal controls		In depressive patients the number and strength of short cort...... In depressive patients the number and strength of short cortex functional connections were significantly larger for the left than for the right hemisphere More...
functional connectivity (FC)	Zhou, 2010	patients and normal controls		All of the altered FCs (functional connectivities) associate...... All of the altered FCs (functional connectivities) associated with the component regions increased in MDD. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
short-range left hemisphere functional connections		Alpha wave(alpha)	neurobiological system	Fingelkurts, 2007	patients and normal controls		Some of the functional connections were positively correlate...... Some of the functional connections were positively correlated with the severity of depression, thus being predictive. These were short-range left hemisphere functional connections for the alpha frequency band More...
short-range anterior functional connections		Alpha wave(alpha frequency band)	neurobiological system	Fingelkurts, 2007	patients and normal controls		Some of the functional connections were positively correlate...... Some of the functional connections were positively correlated with the severity of depression, thus being predictive. These were short-range anterior functional connections for the alpha frequency band More...
short-range posterior functional connections		Alpha wave(alpha frequency band)	neurobiological system	Fingelkurts, 2007	patients and normal controls		These were short-range posterior functional connections for ...... These were short-range posterior functional connections for the alpha frequency band More...
short-range anterior functional connections		Theta wave(theta)	neurobiological system	Fingelkurts, 2007	patients and normal controls		Some of the functional connections were positively correlate...... Some of the functional connections were positively correlated with the severity of depression, thus being predictive. These were short-range anterior functional connections for the theta frequency band More...
functional connectivity (FC) in adaptive control		lateral prefrontal cortices(bilateral lateral prefrontal cortices)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TPN (task-positive networks) the increased FCs were p...... In the TPN (task-positive networks) the increased FCs were primarily located in the bilateral lateral prefrontal cortices and the inferior parietal lobes, which have been implicated in attention and adaptive control. More...
functional connectivity (FC) involved in adaptive control		inferior parietal lobes(inferior parietal lobes)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TPN (task-positive networks) the increased FCs were p...... In the TPN (task-positive networks) the increased FCs were primarily located in the bilateral lateral prefrontal cortices and the inferior parietal lobes, which have been implicated in attention and adaptive control. More...
functional connectivity (FC) involved in emotional regulation		medial orbitofrontal cortex(medial orbitofrontal cortex)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...
functional connectivity (FC) involved in episodic memory		medial orbitofrontal cortex(medial orbitofrontal cortex)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...
functional connectivity (FC) involved in self-reflection		medial orbitofrontal cortex(medial orbitofrontal cortex)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...
functional connectivity (FC) involved in emotional regulation		Posterior cingulate cortex(posterior cingulate cortex)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...
functional connectivity (FC) involved in episodic memory		Posterior cingulate cortex(posterior cingulate cortex)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...
functional connectivity (FC) involved in self-reflection		Posterior cingulate cortex(posterior cingulate cortex)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web