MK4MDD

Molecule Report

Basic Information
Name Fatty Acids
Description Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid.
MeSH ID D005227
No. of Studies (Positive/Negative) 2(2/0) Help

Positive relationship between Fatty Acids and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
fatty acid Conklin, 2010 patients and normal controls In the n-6 fatty acid family, the ratio of 20:3(n-6)/18:2(n-...... In the n-6 fatty acid family, the ratio of 20:3(n-6)/18:2(n-6) was higher in patients than in control groups, whereas the ratio of 20:4(n-6)/20:3(n-6) was relatively decreased in patients. Lastly, a significant negative correlation between age and the ratio of 20:4(n-6) to 22:6(n-3) was found in patients, but not in controls. Taken together, decreases in 22:6(n-3) may be caused, at least in part, by the diminished formation of 20:5(n-3), which is derived from 20:4(n-3) through a Delta5 desaturase reaction. More...
saturated fatty acids (SFAs) Assies, 2010 patients and normal controls In plasma and erythrocytes of patients with MDD-R the concen...... In plasma and erythrocytes of patients with MDD-R the concentrations of the SFAs with a chain length > 20 carbon (C) atoms, were significantly lower than in the controls. In contrast, the concentrations of the shorter chain members (< or = 18C) of the SFAs were significantly higher in the patients. More...

Positive relationships between Fatty Acids and other components at different levels (count: 0) Help
Positive relationship network of Fatty Acids in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between Fatty Acids and MDD (count: 0)
Negative relationships between Fatty Acids and other components at different levels (count: 0) Help