Molecule Report

Basic Information

Name	Docosahexaenoic Acids
Description	C22-unsaturated fatty acids found predominantly in FISH OILS.
MeSH ID	D004281
No. of Studies (Positive/Negative)	2(2/0)

Positive relationship between Docosahexaenoic Acids and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
docosahexaenoic acid (DHA)	McNamara, 2007	patients and normal controls		After correction for multiple comparisons, the omega-3 fatty...... After correction for multiple comparisons, the omega-3 fatty acid DHA was the only fatty acid that was significantly different (-22%) in the postmortem orbitofrontal cortex of MDD patients relative to normal controls. More...

Positive relationships between Docosahexaenoic Acids and other components at different levels (count: 3)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Relation Description
Name in Literature	Related Components
docosahexaenoic acid		Anterior cingulate cortex(anterior cingulate)	brain morphology and function	Sublette, 2009	patients only	Docosahexaenoic acid (22:6n-3), arachidonic acid (20:4n-6), ...... Docosahexaenoic acid (22:6n-3), arachidonic acid (20:4n-6), and eicosapentaenoic acid (20:5n-3) were assessed as a percentage of total phospholipid PUFA (DHA%, AA%, and EPA%, respectively). DHA% correlated negatively with rCMRglu (cerebral metabolic rates of glucose) in prefrontal cortex and anterior cingulate. More...
docosahexaenoic acid		Prefrontal cortex(prefrontal cortex)	brain morphology and function	Sublette, 2009	patients only	Docosahexaenoic acid (22:6n-3), arachidonic acid (20:4n-6), ...... Docosahexaenoic acid (22:6n-3), arachidonic acid (20:4n-6), and eicosapentaenoic acid (20:5n-3) were assessed as a percentage of total phospholipid PUFA (DHA%, AA%, and EPA%, respectively). DHA% correlated negatively with rCMRglu (cerebral metabolic rates of glucose) in prefrontal cortex and anterior cingulate. More...
docosahexaenoic acid		Temporo-parietal connection(temporoparietal cortex)	brain morphology and function	Sublette, 2009	patients only	Docosahexaenoic acid (22:6n-3), arachidonic acid (20:4n-6), ...... Docosahexaenoic acid (22:6n-3), arachidonic acid (20:4n-6), and eicosapentaenoic acid (20:5n-3) were assessed as a percentage of total phospholipid PUFA (DHA%, AA%, and EPA%, respectively). DHA% and AA% correlated positively with rCMRglu (cerebral metabolic rates of glucose) in temporoparietal cortex. More...

Positive relationship network of Docosahexaenoic Acids in MK4MDD

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationship between Docosahexaenoic Acids and MDD (count: 0)

Negative relationships between Docosahexaenoic Acids and other components at different levels (count: 0)