MK4MDD

Signs Report

Basic Information
Name Coronary flow reserve
Description "Coronary flow reserve (CFR) is the ratio of maximum flow during stress (in response to adenosine in the present study) to flow at rest measured in milliliters per minute per gram of tissue, an integrated measure of whole coronary circulation. In the absence of coronary stenosis, CFR provides an index of coronary vasodilator capacity and microvascular function. (Vaccarino et al.,2009; PMID: 19822823)"
No. of Studies (Positive/Negative) 1 (1/0) Help

Positive relationship between Coronary flow reserve and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
coronary flow reserve Vaccarino, 2009 patients and normal controls Among the dizygotic twin pairs discordant for MDD, the CFR was 14% lower in the twins with MDD than in their brothers without MDD (2.36 vs 2.74) (P = .03). This association was not present in the monozygotic discordant pairs who were genetically matched (2.86 vs 2.64) (P = .19). The zygosity-MDD interaction after adjustment was significant (P = .006). The CFR in the dizygotic twins with MDD was also lower than in the control twins. Among the dizygotic twin pairs discordant for MDD, the CFR w...... Among the dizygotic twin pairs discordant for MDD, the CFR was 14% lower in the twins with MDD than in their brothers without MDD (2.36 vs 2.74) (P = .03). This association was not present in the monozygotic discordant pairs who were genetically matched (2.86 vs 2.64) (P = .19). The zygosity-MDD interaction after adjustment was significant (P = .006). The CFR in the dizygotic twins with MDD was also lower than in the control twins. More...

Positive relationships between Coronary flow reserve and other components at different levels (count: 0) Help
Positive relationship network of Coronary flow reserve in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Coronary flow reserve and MDD (count: 0)
Negative relationships between Coronary flow reserve and other components at different levels (count: 0) Help