Brain Morphology and Function Report

Name	Cognitive control network
Brain Morphology	The cognitive control network (CCN), serves attention demanding cognitive tasks and exhibits activity increases in frontal and parietal regions associated with top-down modulation of attention and working memory tasks.
Brain Function	The CCN is involved in decision making and conflict resolution and is known to be impaired in depression. A number of previous studies have found depression-related abnormalities in the CCN, mostly involving decreased task-related activity. Other studies have identified increased task-related "effective" connectivity of the dorsolateral prefrontal cortex (DLPFC) and dorsal cingulate in depression (PMID: 20534464).
No. of Studies (Positive/Negative)	1(1/0)

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
cognitive control network		dorsal medial prefrontal cortex region(dorsal medial prefrontal cortex region)	brain morphology and function	Sheline, 2010	patients and normal controls		Three different brain networks--the cognitive control networ...... Three different brain networks--the cognitive control network, default mode network, and affective network--were investigated. Compared with controls, in depressed subjects each of these three networks had increased connectivity to the same bilateral dorsal medial prefrontal cortex region More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web