Signs Report

Name	Blood pressure (BP)
Description	Blood pressure (BP) is the pressure exerted by circulating blood upon the walls of blood vessels, and is one of the principal vital signs. During each heartbeat, BP varies between a maximum (systolic) and a minimum (diastolic) pressure.
No. of Studies (Positive/Negative)	8 (8/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
blood pressure	Lederbogen, 2003	patients and normal controls	125.5 SD=14.7 versus 119.6 SD=13.3 mmHg, P-value <0.05	Depressed patients not receiving antihypertensive medication...... Depressed patients not receiving antihypertensive medication had higher mean 24 h systolic blood pressure levels than non-depressed comparison subjects (125.5+/-14.7 versus 119.6+/-13.3 mmHg, P<0.05). More...
blood pressure (BP)	Volkers, 2003	patients and normal controls		The mean HR and DBP level and the respiratory frequency were...... The mean HR and DBP level and the respiratory frequency were higher in the patient group than in the control group. More...
blood pressure	Davydov, 2007	patients and normal controls		The patients showed higher general sympathetic activity (hig...... The patients showed higher general sympathetic activity (high levels of blood pressure, low-frequency heart rate variability) and lower parasympathetic-related activity (high heart rate and reduced high frequency heart rate variability) More...
blood pressures	Arslan, 2008	patients and normal controls	120/72 vs. 109/65 mmHg; P-value < or = 0.001	Mean SBP(systolic blood pressures) and DBP(diastolic blood p...... Mean SBP(systolic blood pressures) and DBP(diastolic blood pressures) were higher in MD group (120/72 vs. 109/65 mmHg; p < or = 0.001). More...
systolic blood pressure	Salomon, 2009	patients and normal controls		Depressed participants exhibited significantly less systolic...... Depressed participants exhibited significantly less systolic blood pressure during speech than controls. More...
diastolic blood pressure	Klatzkin, 2010	patients and normal controls		women with prior MDD showed exaggerated diastolic blood pres...... women with prior MDD showed exaggerated diastolic blood pressure responses to stress versus never depressed women More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
systolic blood pressures		Nitric oxide(nitric oxide (NO))	molecule	Arslan, 2008	patients and normal controls	r = -0.50; P-value < 0.01	There was a significant negative correlation between plasma ...... There was a significant negative correlation between plasma NO levels and SBP(systolic blood pressures) in MD group (r = -0.50; p < 0.01). More...
blood pressure		White matter(white matter)	brain morphology and function	Hoptman, 2009	patients only		white matter integrity assessed by diffusion tensor imaging ...... white matter integrity assessed by diffusion tensor imaging (fractional anisotropy, FA). Significant associations between FA and blood pressure were detected throughout the anterior cingulate and in multiple frontostriatal and frontotemporal regions. More...
blood pressure		White matter(white matter hyperintensities (WMH))	brain morphology and function	Colloby, 2011	patients and normal controls	age-corrected partial correlation r' = 0.31-0.35, P-value<0.05	An association between orthostatic systolic blood pressure d...... An association between orthostatic systolic blood pressure drop and WMH volumes in temporal and parietal regions was found in the depression group (age-corrected partial correlation r' = 0.31-0.35, P<0.05). More...
blood pressure (BP)		Increased agitation(agitation)	symptoms	Volkers, 2003	patients and normal controls		motor activity parameters and cardiovascular measures of the...... motor activity parameters and cardiovascular measures of the patients were related to agitation and retardation and overall, patients with lower motor activity levels demonstrated lower SBP levels. More...
blood pressure (BP)		Low energy(psychomotor retardation)	symptoms	Volkers, 2003	patients and normal controls		motor activity parameters and cardiovascular measures of the...... motor activity parameters and cardiovascular measures of the patients were related to agitation and retardation and overall, patients with lower motor activity levels demonstrated lower SBP levels. More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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