MK4MDD

Symptoms Report

Basic Information
Name suicide attempt (SA)
Description "Epidemiological studies have recognized a genetic diathesis for suicidal behavior, which is independent of other psychiatric disorders. Genome-wide association studies (GWAS) on suicide attempt (SA) and ideation have failed to identify specific genetic variants."
No. of Studies (Positive/Negative) 2 (1/1) Help

Positive relationship between suicide attempt (SA) and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
suicide attempt (SA) Mullins N, 2014 Patients and nomal controls P=0.013 The RADIANT, GSK-Munich, and BACCs validation datasets were ...... The RADIANT, GSK-Munich, and BACCs validation datasets were merged into a single dataset in order to increase the precision of prediction. This sample has the same characteristics as the meta-analysis (n=3,270) and includes 426 SA cases. Scores for MDD, BIP and SCZ from the PGC were tested as predictors of SA in this combined validation dataset (Supplementary material). PGC-MDD scores showed significant predictive ability for SA, the largest R2 being 0.3% at PT<0.3 (P=0.013) More...

Positive relationships between suicide attempt (SA) and other components at different levels (count: 4) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of suicide attempt (SA) in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between suicide attempt (SA) and MDD (count: 0)
Negative relationships between suicide attempt (SA) and other components at different levels (count: 60) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment