SNP Report

Name	rs948854 dbSNP Ensembl
Location	Chrchr11:68450203(Forward)
Variant Alleles	C/T
Ancestral Allele	C
Annotation	upstream_gene_variant
Consequence to Transcript	upstream_gene_variant(ENST00000265643, ENST00000538401)
No. of Studies (Positive/Negative)	1 (1/0)

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
rs948854		Hypothalamic-pituitary-adrenal axis(HPA-axis)	neurobiological system	Unschuld, 2010	patients and normal controls		This allele was associated with higher HPA-axis activity at ...... This allele was associated with higher HPA-axis activity at admission More...
rs948854		Vegetative symptoms(severe vegetative symptoms)	symptoms	Unschuld, 2010	patients and normal controls		In premenopausal female MDD patients, the same allele of rs9...... In premenopausal female MDD patients, the same allele of rs948854 was associated with more severe vegetative but not cognitive depressive symptoms at discharge and worse treatment response on antidepressant medication. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
GAL	galanin/GMAP prepropeptide	Literature-origin; SNP mapped	2(1/1)