MK4MDD

SNP Report

Basic Information
Name rs6265 dbSNP Ensembl
Location Chrchr11:27658369(Forward)
Variant Alleles C/T
Ancestral Allele C
No. of Studies (Positive/Negative) 9 (5/4) Help

Positive relationship between rs6265 and MDD (count: 4)
Reference Research Type Statistical Result Relation Description Help
Suchanek, 2011 patients and normal controls The val/val genotype was more frequent in depressed individu...... The val/val genotype was more frequent in depressed individuals compared to the control group, both in total analysis and after stratification by sex. The val allele is connected with a higher risk of MDD-R development in men than in women. More...
Bosker, 2010 patients and normal controls Significance of candidate SNPs for MDD identified from the l...... Significance of candidate SNPs for MDD identified from the literature within the GAIN MDD GWAS More...
Ribeiro L, 2007 Patients and nomal controls P=0.005 The single nucleotide polymorphism (Val66Met), which has bee...... The single nucleotide polymorphism (Val66Met), which has been shown to have functional and behavioral effects, was genotyped in 284 depressed participants and 331 controls, showing association with depression (P=0.005) More...
Licinio, 2009 patients and normal controls Association analyses of patients with MDD and controls showe...... Association analyses of patients with MDD and controls showed that 6 SNPs were associated with MDD (rs12273539, rs11030103, rs6265, rs28722151, rs41282918, and rs11030101) More...

Relationships between rs6265 and other components at different levels (count: 2) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of rs6265 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between rs6265 and MDD (count: 3)
Reference Research Type Statistical Result Relation Description
Surtees PG, 2007 Patients and nomal controls In this population based study we found no evidence to suppo...... In this population based study we found no evidence to support an association between the BDNF gene Val66Met polymorphism and mood status More...
Pae CU, 2012 Patients and nomal controls rs10835210 CA and rs11030101 AT genotype frequencies were hi...... rs10835210 CA and rs11030101 AT genotype frequencies were higher in BD and schizophrenia patients than in healthy and MD subjects. No significant association was found with clinical improvement More...
Januar, 2015 Patients and nomal controls P=0.126 The frequencies of the BDNF SNPs (Table 2) were not signific...... The frequencies of the BDNF SNPs (Table 2) were not significantly different from those predicted under Hardy¨CWeinberg equilibrium (P>0.14 for all SNPs) More...

Negative relationships between rs6265 and other components at different levels (count: 1) Help


rs6265 related genes (count: 1)