MK4MDD

SNP Report

Basic Information
Name rs3766688 dbSNP Ensembl
Location Chrchr1:175182814(Forward)
Variant Alleles T/C
Ancestral Allele T
No. of Studies (Positive/Negative) 1 (0/1) Help

Positive relationship between rs3766688 and MDD (count: 0)
Relationships between rs3766688 and other components at different levels (count: 0) Help
Negative relationships between rs3766688 and MDD (count: 1)
Reference Research Type Statistical Result Relation Description
consortium, 2015 Patients and nomal controls p=1.34E-04 We replicated the associations by genotyping the same 12 SNP...... We replicated the associations by genotyping the same 12 SNPs in a separate Han Chinese cohort of 3,231 cases with recurrentMDD, and 3,186 controls (both sexes). Two SNPs at the peaks of association for SIRT1 and LHPP loci (rs12415800 and rs35936514, respectively) for MDD in the CONVERGE samples were significantly associated with MDD (Table 1). Analysis of the combined samples gave P values for association with MDD at these two SNPs of 2.53E-10 and 6.45E-12, respectively. Extended Data Table 2 shows the genotype distribution and P values for tests of violation of the Hardy¨CWeinberg equilibrium in both the CONVERGE samples and the replication cohort at both SNPs. More...

Negative relationships between rs3766688 and other components at different levels (count: 0) Help
rs3766688 related genes (count: 0)