MK4MDD

SNP Report

Basic Information
Name rs34867163 dbSNP Ensembl
Location Chrchr11:75351503(Forward)
Variant Alleles A/G
Ancestral Allele A
Annotation regulatory_region_variant
Consequence to Transcript regulatory_region_variant(ENST00000420843, ENST00000360025, ENST00000533255)
No. of Studies (Positive/Negative) 1 (1/0) Help

Positive relationship between rs34867163 and MDD (count: 1)
Reference Research Type Statistical Result Relation Description Help
Chang, 2015 Patients and nomal controls p=0.024; OR[95% CI]=6.5 (1.29¨C32.82) The genotype distributions of ?132C>T and IVS1+85T>C deviate...... The genotype distributions of ?132C>T and IVS1+85T>C deviated significantly from HWE in MDD but not in normal subjects (Table 2); those of the other SNPs were in HWE. Thegenotype distribution of ?132C>T and IVS1+85T>C differed significantly between MDD and normal subjects; the % of MDD patients who were ?132TT homozygotes was 5.1%, which was higher than the 1.0% of normal subjects with this status (p=0.021, odds ratio (OR)=6.81 with 1.34¨C34.58 of 95% confidence interval (CI); Table 2). Similarly, the percentage in the MDD group contained a higher percentage of IVS1+85CC homozygotes than did the normal group (5.0% vs 1.0%, p=0.024, OR (95% CI)=6.5 (1.29¨C32.82)). However, these differences were not significant after correction for multiple comparisons. More...

Relationships between rs34867163 and other components at different levels (count: 0) Help
Positive relationship network of rs34867163 in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between rs34867163 and MDD (count: 0)
Negative relationships between rs34867163 and other components at different levels (count: 0) Help
rs34867163 related genes (count: 0)