SNP Report

Name	rs2433320 dbSNP Ensembl
Location	Chrchr4:95370805(Forward)
Variant Alleles	G/A
Ancestral Allele	G
Annotation	downstream_gene_variant; upstream_gene_variant
Consequence to Transcript	downstream_gene_variant(ENST00000356560) upstream_gene_variant(ENST00000317968, ENST00000318007, ENST00000359265, ENST00000380180, ENST00000437932, ENST00000450793, ENST00000503974, ENST00000504489, ENST00000509333, ENST00000512274, ENST00000514830, ENST00000538141, ENST00000542407)
No. of Studies (Positive/Negative)	1 (1/0)

Reference	Research Type	Statistical Result	Relation Description
Liu, 2008	patients and normal controls	genotype: P-value = 0.007; allele:P-value = 0.007	We observed significant allele (p = 0.007) and genotype (p =...... We observed significant allele (p = 0.007) and genotype (p = 0.007) association with rs2433320, and the G allele of rs2433320 was significantly overrepresented in control subjects in comparison with MDD patients. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
PDLIM5	PDZ and LIM domain 5	Literature-origin; SNP mapped	1(1/0)