MK4MDD

SNP Report

Basic Information
Name rs1930437 dbSNP Ensembl
Location Chrchr1:206473084(Forward)
Variant Alleles C/A
Ancestral Allele C
No. of Studies (Positive/Negative) 1 (1/0) Help

Positive relationship between rs1930437 and MDD (count: 1)
Reference Research Type Statistical Result Relation Description Help
Traks T, 2015 Patients and nomal controls P-value(GGG) =0.0022,OR(GGG)=1.38,95% confidence intervals (CI)(GGG)=(1.12¨C1.70),correct P values(GGG)=0.0479;P-value(GAT) =0.0015,OR(GAT)=0.72,95% confidence intervals (CI)(GAT)=(0.59¨C0.88),correct P values(GGG)=0.0332. Two haplotypes of Block 1 (consisting of rs1930438, rs227490...... Two haplotypes of Block 1 (consisting of rs1930438, rs2274902, and rs1930437) were associated with MDD.haplotypes GAT and GGG with respective P values of 0.0015 (OR 0.72 (CI: 0.59¨C0.88)) and 0.0022 (OR 1.38 (CI: 1.12¨C1.70)) that remained below the significance threshold after corrections for multiple testing (permutation P values 0.0332 and 0.0479, respectively). While the frequency of the GAT haplotype was lower among MDD patients (41.3%) compared to control individuals (49.3%) thus indicating a possible protective effect, the frequencies of GGG haplotype were reversed (38.9% in MDD group and 31.5% in control group), thereby suggesting a possible promoting effect, that is, risk haplotype. More...

Relationships between rs1930437 and other components at different levels (count: 0) Help
Positive relationship network of rs1930437 in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between rs1930437 and MDD (count: 0)
Negative relationships between rs1930437 and other components at different levels (count: 0) Help
rs1930437 related genes (count: 0)