SNP Report

Name	rs16944 dbSNP Ensembl
Location	Chrchr2:113594867(Forward)
Variant Alleles	A/G
Ancestral Allele	A
Annotation	upstream_gene_variant
Consequence to Transcript	upstream_gene_variant(ENST00000263341, ENST00000416750, ENST00000418817, ENST00000432018, ENST00000477398, ENST00000487639, ENST00000491056, ENST00000496280)
No. of Studies (Positive/Negative)	1 (1/0)

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
rs16944		Amygdala(amygdala)	brain morphology and function	Baune, 2010	patients only		The imaging analyses show that the number of G-alleles in bo...... The imaging analyses show that the number of G-alleles in both SNPs (rs16944 and rs1143643) was associated with reduced responsiveness of the amygdala and ACC to emotional stimulation. More...
rs16944		Anterior cingulate cortex(ACC)	brain morphology and function	Baune, 2010	patients only		The imaging analyses show that the number of G-alleles in bo...... The imaging analyses show that the number of G-alleles in both SNPs (rs16944 and rs1143643) was associated with reduced responsiveness of the amygdala and ACC to emotional stimulation. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
IL1B	interleukin 1, beta	Literature-origin; SNP mapped; Protein mapped	3(2/1)