SNP Report

Name	rs1045642 dbSNP Ensembl
Location	Chrchr7:87138645(Forward)
Variant Alleles	A/G/T
Ancestral Allele	G
Annotation	3_prime_UTR_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant; synonymous_variant; upstream_gene_variant
Consequence to Transcript	3_prime_UTR_variant(ENST00000415096) nc_transcript_variant(ENST00000475929, ENST00000488737) NMD_transcript_variant(ENST00000415096) non_coding_exon_variant(ENST00000475929, ENST00000488737) synonymous_variant(ENST00000265724, ENST00000543898) upstream_gene_variant(ENST00000491360)
No. of Studies (Positive/Negative)	1 (1/0)

Reference	Research Type	Statistical Result	Relation Description
Fujii T, 2012	patients and normal controls	chi(2) = 4.5, df = 1, P-value = 0.034, odds ratio [OR] 1.16, 95% confidential interval [CI] 1.01-1.34	The minor T3435 allele was significantly increased in MDD pa...... The minor T3435 allele was significantly increased in MDD patients than in the controls (chi(2) = 4.5, df = 1, p = 0.034, odds ratio [OR] 1.16, 95% confidential interval [CI] 1.01-1.34). Homozygotes for the T3435 allele was significantly more common in patients than in the controls (chi(2) = 7.5, df = 1, p = 0.0062, OR 1.43, 95%CI 1.11-1.85). More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Literature-origin; SNP mapped	1(1/0)