MK4MDD

Protein Report

Basic Information
Protein Name insulin-like growth factor I (IGF-I)
UniPortKB P05019
No. of Studies (Positive/Negative) 1 (0/1) Help
Type Literature-origin
Positive relationship between insulin-like growth factor I (IGF-I) and MDD (count: 0)
Positive relationships between insulin-like growth factor I (IGF-I) and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment

Positive relationship network of insulin-like growth factor I (IGF-I) in MK4MDD
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network_footer.jsp Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between insulin-like growth factor I (IGF-I) and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
insulin-like growth factor I (IGF-I) Kopczak, 2015 patients only F(1,72)=4.13, p=0.046 IGF-I levels at admission were significantly higher in non-r...... IGF-I levels at admission were significantly higher in non-remitters compared to remitters (F(1,72)=4.13, p=0.046, see Table 2b). After 6 weeks of psychopharmacological treatment, higher IGF-I levels persisted in non-remitters, although the difference did not reach statistical significance (see Table 2b). IGF-I levels remained stable during treatment when analyzing all patients.No significant changes in IGF-I levels during treatment comparing remitters and non-remitters were observed in a repeated measures analysis (Greenhouse┬ĘCGeisser, F(1,72)=0.10, p=0.75). More...

Negative relationships between insulin-like growth factor I (IGF-I) and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment

Related Gene Info
Gene Symbol Gene Name Type No. of Studies (Positive/Negative) Add to Relationship Set
IGF1 insulin-like growth factor 1 (somatomedin C) Protein mapped 0 (0/0)