Protein Report

Protein Name	cAMP-dependent protein kinase type I-alpha regulatory subunit
UniPortKB	P10644
No. of Studies (Positive/Negative)	1 (1/0)
Type	Literature-origin

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
PKA regulatory Ialpha	Shelton, 2009	patients and normal controls		The MDD sample exhibited significantly lower protein express...... The MDD sample exhibited significantly lower protein expression of PKA regulatory Ialpha (RIalpha), PKA catalytic alpha (Calpha) and Cbeta, PKCbeta1, and PKCepsilon relative to controls. More...

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network_footer.jsp Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Gene Symbol	Gene Name	Type	No. of Studies (Positive/Negative)	Add to Relationship Set
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha	Literature-origin; Protein mapped	1 (1/0)