Gene Report

Basic Information

Approved Symbol	VPS13A
Approved Name	vacuolar protein sorting 13 homolog A (S. cerevisiae)
Previous Symbol	CHAC
Previous Name	chorea acanthocytosis, "vacuolar protein sorting 13A (yeast)"
Symbol Alias	KIAA0986
Location	9q21
Position	chr9:79792361-80032399 (+)
External Links	Entrez Gene: 23230 Ensembl: ENSG00000197969 UCSC: uc004akr.3 HGNC ID: 1908
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between VPS13A and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
VPS13A	Sequeira A, 2009	patients and nomal controls	Group: P-value=0.023, F=4.5; Substance: P-value=0.008, F=8.6	Genes differentially expressed after an ANCOVA analysis betw...... Genes differentially expressed after an ANCOVA analysis between the three groups(C = control, S = suicide, SMD = suicide with major depression). More...

Positive relationships between VPS13A and other components at different levels (count: 1)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Name in Literature	Related Components
VPS13A		Suicide(suicide)	symptoms	Sequeira A, 2009	patients and nomal controls	Group: P-value=0.023, F=4.5; Substance: P-value=0.008, F=8.6	Genes differentially expressed after an ANCOVA analysis betw...... Genes differentially expressed after an ANCOVA analysis between the three groups(C = control, S = suicide, SMD = suicide with major depression). More...

Positive relationship network of VPS13A in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between VPS13A and MDD (count: 0)

Negative relationships between VPS13A and other components at different levels (count: 0)

VPS13A related SNPs in MK4MDD (count: 0)

VPS13A related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Vacuolar protein sorting-associated protein 13A	Q96RL7	0(0/0)	Gene mapped

VPS13A related GO terms (count: 9)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0008219	cell death	biological process	IEA
GO:0005622	intracellular	cellular component	NAS[11381254]
GO:0007626	locomotory behavior	biological process	IEA
GO:0035176	social behavior	biological process	IEA
GO:0007399	nervous system development	biological process	IEA
GO:0005515	protein binding	molecular function	IPI[17474147]
GO:0015031	protein transport	biological process	IEA
GO:0006895	Golgi to endosome transport	biological process	NAS[11381253]
GO:0008104	protein localization	biological process	NAS[11381254]

VPS13A related KEGG pathways (count: 0)

VPS13A related BioCarta pathways (count: 0)

VPS13A related Reactome pathways (count: 0)

VPS13A related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms