MK4MDD

Molecule Report

Basic Information
Name Thyroxine
Description The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines ( MONOIODOTYROSINE) and the coupling of iodotyrosines ( DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
MeSH ID D013974
No. of Studies (Positive/Negative) 1(1/0) Help

Positive relationship between Thyroxine and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
tyrosine Kurup, 2002 patients and normal controls There was increase in tyrosine and tyrosine catabolites, and...... There was increase in tyrosine and tyrosine catabolites, and a reduction in tryptophan and its catabolites, in the serum in the depressive phase of bipolar mood disorder and major depressive disorder. More...

Positive relationships between Thyroxine and other components at different levels (count: 0) Help
Positive relationship network of Thyroxine in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between Thyroxine and MDD (count: 0)
Negative relationships between Thyroxine and other components at different levels (count: 0) Help