Gene Report

Basic Information

Approved Symbol	TTLL2
Approved Name	tubulin tyrosine ligase-like family, member 2
Previous Symbol	C6orf104
Previous Name	chromosome 6 open reading frame 104
Symbol Alias	NYD-TSPG, dJ366N23.3
Location	6q27
Position	chr6:167738574-167756177 (+)
External Links	Entrez Gene: 83887 Ensembl: ENSG00000120440 UCSC: uc003qvs.1 HGNC ID: 21211
No. of Studies (Positive/Negative)	1(0/1)
Type	Literature-origin

Positive relationships between TTLL2 and MDD (count: 0)

Positive relationships between TTLL2 and other components at different levels (count: 0)

Positive relationship network of TTLL2 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between TTLL2 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
TTLL2	Wray, 2010	patients and normal controls		Top ten ranked genes from gene-based test for genes +/-50 kb...... Top ten ranked genes from gene-based test for genes +/-50 kb from start and stop positions More...

Negative relationships between TTLL2 and other components at different levels (count: 0)

TTLL2 related SNPs in MK4MDD (count: 0)

TTLL2 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Probable tubulin polyglutamylase TTLL2	Q9BWV7	0(0/0)	Gene mapped

TTLL2 related GO terms (count: 4)

ID	Name	Type	Evidence
Literature-origin GO terms
GO:0032553	ribonucleotide binding	molecular function	IEA
GO:0032553	ribonucleotide binding	molecular function	IEA

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0006464	cellular protein modification process	biological process	IEA
GO:0004835	tubulin-tyrosine ligase activity	molecular function	IEA

TTLL2 related KEGG pathways (count: 0)

TTLL2 related BioCarta pathways (count: 0)

TTLL2 related Reactome pathways (count: 0)

TTLL2 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Literature-origin GO terms

Gene mapped GO terms