MK4MDD

Gene Report

Basic Information
Approved Symbol STAT3
Approved Name signal transducer and activator of transcription 3 (acute-phase response factor)
Symbol Alias APRF
Location 17q21
Position chr17:40540578-40540579 (-)
External Links Entrez Gene: 6774
Ensembl: ENSG00000168610
UCSC: uc002hzl.1
HGNC ID: 11364
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between STAT3 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
STAT3 Jansen R, 2015 patients and normal controls P-value=0.000276;FDR=0.0975;beta=0.233 we found 129 genes (142 probesets) differentially expressed ...... we found 129 genes (142 probesets) differentially expressed between the control and current MDD groups (FDR<0.1) More...

Positive relationships between STAT3 and other components at different levels (count: 0) Help
Positive relationship network of STAT3 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between STAT3 and MDD (count: 0)
Negative relationships between STAT3 and other components at different levels (count: 0) Help
STAT3 related SNPs in MK4MDD (count: 0)
STAT3 related proteins in MK4MDD (count: 0)
STAT3 related GO terms (count: 78)
STAT3 related KEGG pathways (count: 6)
STAT3 related BioCarta pathways (count: 10)
STAT3 related Reactome pathways (count: 4)
STAT3 related interactors from protein-protein interaction data in HPRD (count: 102)