MK4MDD

Gene Report

Basic Information
Approved Symbol SRSF5
Approved Name serine/arginine-rich splicing factor 5
Previous Symbol SFRS5
Previous Name "splicing factor, arginine/serine-rich 5"
Symbol Alias SRP40, HRS
Name Alias "SR splicing factor 5"
Location 14q24
Position chr14:70238634-70238722 (+)
External Links Entrez Gene: 6430
Ensembl: ENSG00000100650
UCSC: uc001xlp.3
HGNC ID: 10787
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between SRSF5 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
SRSF5 Mostafavi S, 2013 patients and normal controls P-value=1.64E-04
SRSF5 Jansen R, 2015 patients and normal controls P-value(MDD Affymetrix U219)=0.0059;P-value(MDD RNA-seq)=0.00016;P-value(MDD meta)=1.5E-05;FDR (MDD meta)=0.065; "Mostafavi et al studied gene expression differences between...... "Mostafavi et al studied gene expression differences between 463 MDD cases and 459 controls using RNA-seq measurements. The P-values and directions of effects from this study were compared and meta-analyzed with our findings.When meta analyzing the P-values from the two studies, (weighted Z-score method), 12 genes were differentially expressed at FDRo0.1 (CALM1, FCRL6, APOBEC3G, SRSF5, RAP2B, PIPOX, PRR5L, HAGHL, ARL4C, NMUR1, KLRD1 and KCNJ2)" More...

Positive relationships between SRSF5 and other components at different levels (count: 0) Help
Positive relationship network of SRSF5 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SRSF5 and MDD (count: 0)
Negative relationships between SRSF5 and other components at different levels (count: 0) Help
SRSF5 related SNPs in MK4MDD (count: 0)
SRSF5 related proteins in MK4MDD (count: 0)
SRSF5 related GO terms (count: 22)
SRSF5 related KEGG pathways (count: 0)
SRSF5 related BioCarta pathways (count: 0)
SRSF5 related Reactome pathways (count: 0)
SRSF5 related interactors from protein-protein interaction data in HPRD (count: 0)