MK4MDD

Gene Report

Basic Information
Approved Symbol S1PR1
Approved Name sphingosine-1-phosphate receptor 1
Previous Symbol EDG1
Previous Name "endothelial differentiation, sphingolipid G-protein-coupled receptor, 1"
Symbol Alias edg-1, D1S3362, CD363
Location 1p21
Position chr1:101705690-101707076 (+)
External Links Entrez Gene: 1901
Ensembl: ENSG00000170989
UCSC: uc001dud.2
HGNC ID: 3165
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between S1PR1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
S1PR1 Jansen R, 2015 patients and normal controls P-value=0.000294;FDR=0.0981;beta=-0.22 we found 129 genes (142 probesets) differentially expressed ...... we found 129 genes (142 probesets) differentially expressed between the control and current MDD groups (FDR<0.1) More...

Positive relationships between S1PR1 and other components at different levels (count: 0) Help
Positive relationship network of S1PR1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between S1PR1 and MDD (count: 0)
Negative relationships between S1PR1 and other components at different levels (count: 0) Help
S1PR1 related SNPs in MK4MDD (count: 0)
S1PR1 related proteins in MK4MDD (count: 0)
S1PR1 related GO terms (count: 38)
S1PR1 related KEGG pathways (count: 1)
S1PR1 related BioCarta pathways (count: 1)
S1PR1 related Reactome pathways (count: 4)
S1PR1 related interactors from protein-protein interaction data in HPRD (count: 7)