MK4MDD

Brain Morphology and Function Report

Basic Information
Name Precuneus
Brain Morphology The precuneus is a part of the superior parietal lobule hidden in the medial longitudinal fissure between the two cerebral hemispheres. It is sometimes described as the medial area of the superior parietal cortex.
Brain Function "It is involved with episodic memory, visuospatial processing, reflections upon self, and aspects of consciousness."
Picture Precuneus From Wiki. Magnify
No. of Studies (Positive/Negative) 9(9/0) Help

Positive relationships between Precuneus and MDD (count: 9)
Name in Literature Reference Research Type Statistical Result Relation Description Help
precuneus Costafreda, 2009 patients and normal controls Decreased grey matter density in precuneus (BA 7) showed the...... Decreased grey matter density in precuneus (BA 7) showed the highest contribution to the diagnosis of depression. More...
precuneus Pizzagalli, 2002 patients and normal controls Depressed subjects showed precuneus hypoactivity. Depressed subjects showed precuneus hypoactivity.
precuneus Grimm, 2009 patients and normal controls Neurally, patients with MDD showed significantly lower signa...... Neurally, patients with MDD showed significantly lower signal intensities in various subcortical and cortical midline regions like the dorsomedial prefrontal cortex (DMPFC), supragenual anterior cingulate cortex, precuneus, ventral striatum (VS), and the dorsomedial thalamus (DMT). More...
precuneus Halari, 2009 patients and normal controls Adolescents with depression compared to healthy controls dem...... Adolescents with depression compared to healthy controls demonstrated reduced activation in precuneus during the Simon task. More...
precuneus Frodl, 2010 patients and normal controls Dorsal anterior cingulate cortex, precuneus, and cerebellum ...... Dorsal anterior cingulate cortex, precuneus, and cerebellum activity showed less connectivity with the OFC in patients than in control subjects More...
precuneus Bluhm, 2009 patients and normal controls Direct comparison showed significantly reduced correlation b...... Direct comparison showed significantly reduced correlation between the P/PCC(precuneus/posterior cingulate cortex) and the bilateral caudate in depression compared with controls and no areas of increased connectivity in the depressed group. More...
precuneus Scheuerecker, 2010 patients and normal controls Depressed patients showed increased activity during emotion ...... Depressed patients showed increased activity during emotion recognition in the precuneus. More...
precuneus Salvadore, 2011 patients and normal controls Relative to the rMDD(currently-remitted) group the dMDD(curr...... Relative to the rMDD(currently-remitted) group the dMDD(currently-depressed participants) group showed reduced GM(gray matter) in the precuneus. More...
precuneus Zhu, 2012 patients and normal controls We observed decreased functional connectivity in the posteri...... We observed decreased functional connectivity in the posterior medial cortex regions (especially the posterior cingulate cortex/precuneus) in MDD patients compared with control subjects. More...

Positive relationships between Precuneus and other components at different levels (count: 3) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Precuneus in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Precuneus and MDD (count: 0)
Negative relationships between Precuneus and other components at different levels (count: 0) Help