MK4MDD

Brain Morphology and Function Report

Basic Information
Name Periaqueductal gray
Brain Morphology Periaqueductal gray (PAG) is the gray matter located around the cerebral aqueduct within the tegmentum of the midbrain.
Brain Function "It plays a role in the descending modulation of pain and in defensive behaviour. The ascending pain and temperature fibers of the spinothalamic tract also send information to the PAG via the spinomesencephalic tract (so-named because the fibers originate in the spine and terminate in the PAG, in the mesencephalon or midbrain)."
No. of Studies (Positive/Negative) 2(2/0) Help

Positive relationships between Periaqueductal gray and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
periaqueductal gray Cannon, 2007 patients and normal controls PAG, 20%, 22% The unipolar-depressives had elevated 5-HTT BP relative to b...... The unipolar-depressives had elevated 5-HTT BP relative to both BD (bipolar-depressives) and HC (healthy-controls) groups in the vicinity of the periaqueductal gray (PAG, 20%, 22%, respectively). More...
periaqueductal gray matter Strigo, 2008 patients and normal controls Subjects with MDD compared with healthy controls showed decr...... Subjects with MDD compared with healthy controls showed decreased activation in periaqueductal gray matter during painful stimulation relative to nonpainful stimulation, More...

Positive relationships between Periaqueductal gray and other components at different levels (count: 0) Help
Positive relationship network of Periaqueductal gray in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Periaqueductal gray and MDD (count: 0)
Negative relationships between Periaqueductal gray and other components at different levels (count: 0) Help