MK4MDD

Gene Report

Basic Information
Approved Symbol PVRL1
Approved Name poliovirus receptor-related 1 (herpesvirus entry mediator C)
Previous Symbol HVEC, ED4
Symbol Alias PRR, PRR1, PVRR1, SK-12, HIgR, CLPED1, CD111, OFC7
Name Alias "nectin"
Location 11q23-q24
Position chr11:119599264-119599435 (-)
External Links Entrez Gene: 5818
Ensembl: ENSG00000110400
UCSC: uc001pwv.3
HGNC ID: 9706
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between PVRL1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PVRL1 Jansen R, 2015 patients and normal controls P-value=0.0000108;FDR=0.0363;beta=0.271 P-values, FDR and betas of 18 genes differentially expressed...... P-values, FDR and betas of 18 genes differentially expressed between control and current MDD groups (FDR<0.05) More...

Positive relationships between PVRL1 and other components at different levels (count: 0) Help
Positive relationship network of PVRL1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PVRL1 and MDD (count: 0)
Negative relationships between PVRL1 and other components at different levels (count: 0) Help
PVRL1 related SNPs in MK4MDD (count: 0)
PVRL1 related proteins in MK4MDD (count: 0)
PVRL1 related GO terms (count: 39)
PVRL1 related KEGG pathways (count: 2)
PVRL1 related BioCarta pathways (count: 0)
PVRL1 related Reactome pathways (count: 3)
PVRL1 related interactors from protein-protein interaction data in HPRD (count: 7)