MK4MDD

Gene Report

Basic Information
Approved Symbol PTX3
Approved Name pentraxin 3, long
Previous Symbol TNFAIP5
Previous Name "pentaxin-related gene, rapidly induced by IL-1 beta", "tumor necrosis factor, alpha-induced protein 5", "pentraxin-related gene, rapidly induced by IL-1 beta"
Symbol Alias TSG-14
Location 3q25
Position chr3:157160769-157161417 (+)
External Links Entrez Gene: 5806
Ensembl: ENSG00000163661
UCSC: uc003fbl.4
HGNC ID: 9692
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between PTX3 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PTX3 Carvalho LA, 2014 patients and normal controls FC=2.3; P-value=0.006 Thirty-four of the 47 monocyte inflammatory-related genes w...... Thirty-four of the 47 monocyte inflammatory-related genes were significantly upregulated and 2 were significantly downregulated as compared to controls More...

Positive relationships between PTX3 and other components at different levels (count: 0) Help
Positive relationship network of PTX3 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PTX3 and MDD (count: 0)
Negative relationships between PTX3 and other components at different levels (count: 0) Help
PTX3 related SNPs in MK4MDD (count: 0)
PTX3 related proteins in MK4MDD (count: 0)
PTX3 related GO terms (count: 16)
PTX3 related KEGG pathways (count: 0)
PTX3 related BioCarta pathways (count: 0)
PTX3 related Reactome pathways (count: 0)
PTX3 related interactors from protein-protein interaction data in HPRD (count: 5)