MK4MDD

Gene Report

Basic Information
Approved Symbol PTGS2
Approved Name prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Symbol Alias COX2
Location 1q25.2-q25.3
Position chr1:186649423-186649559 (-)
External Links Entrez Gene: 5743
Ensembl: ENSG00000073756
UCSC: uc001gsb.3
HGNC ID: 9605
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between PTGS2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PTGS2 Carvalho LA, 2014 patients and normal controls FC=2.1; P-value=0.007 Thirty-four of the 47 monocyte inflammatory-related genes w...... Thirty-four of the 47 monocyte inflammatory-related genes were significantly upregulated and 2 were significantly downregulated as compared to controls More...

Positive relationships between PTGS2 and other components at different levels (count: 0) Help
Positive relationship network of PTGS2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PTGS2 and MDD (count: 0)
Negative relationships between PTGS2 and other components at different levels (count: 0) Help
PTGS2 related SNPs in MK4MDD (count: 0)
PTGS2 related proteins in MK4MDD (count: 0)
PTGS2 related GO terms (count: 81)
PTGS2 related KEGG pathways (count: 5)
PTGS2 related BioCarta pathways (count: 1)
PTGS2 related Reactome pathways (count: 5)
PTGS2 related interactors from protein-protein interaction data in HPRD (count: 5)