Gene Report

Basic Information

Approved Symbol	PROSC
Approved Name	proline synthetase co-transcribed homolog (bacterial)
Previous Name	proline synthetase co-transcribed (bacterial homolog)
Location	8p11.2
Position	chr8:37620101-37637286 (+)
External Links	Entrez Gene: 11212 Ensembl: ENSG00000147471 UCSC: uc003xkh.3 HGNC ID: 9457
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between PROSC and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
PROSC	Aston, 2005	patients and normal controls		Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between PROSC and other components at different levels (count: 0)

Positive relationship network of PROSC in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between PROSC and MDD (count: 0)

Negative relationships between PROSC and other components at different levels (count: 0)

PROSC related SNPs in MK4MDD (count: 0)

PROSC related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Proline synthase co-transcribed bacterial homolog protein	O94903	0(0/0)	Gene mapped

PROSC related GO terms (count: 5)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0005737	cytoplasm	cellular component	NAS[10496079]
GO:0005622	intracellular	cellular component	IDA
GO:0030170	pyridoxal phosphate binding	molecular function	IBA
GO:0008150	biological_process	biological process	ND
GO:0005739	mitochondrion	cellular component	IEA

PROSC related KEGG pathways (count: 0)

PROSC related BioCarta pathways (count: 0)

PROSC related Reactome pathways (count: 0)

PROSC related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms