MK4MDD

Gene Report

Basic Information
Approved Symbol PRF1
Approved Name perforin 1 (pore forming protein)
Symbol Alias PFP, P1, HPLH2
Name Alias "Perforin", "perforin 1 (preforming protein)"
Location 10q22
Position chr10:72362401-72362531 (-)
External Links Entrez Gene: 5551
Ensembl: ENSG00000180644
UCSC: uc001jrf.4
HGNC ID: 9360
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between PRF1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PRF1 Jansen R, 2015 patients and normal controls P-value=0.0000569;FDR=0.066;beta=-0.246 we found 129 genes (142 probesets) differentially expressed ...... we found 129 genes (142 probesets) differentially expressed between the control and current MDD groups (FDR<0.1) More...

Positive relationships between PRF1 and other components at different levels (count: 0) Help
Positive relationship network of PRF1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PRF1 and MDD (count: 0)
Negative relationships between PRF1 and other components at different levels (count: 0) Help
PRF1 related SNPs in MK4MDD (count: 0)
PRF1 related proteins in MK4MDD (count: 0)
PRF1 related GO terms (count: 19)
PRF1 related KEGG pathways (count: 6)
PRF1 related BioCarta pathways (count: 4)
PRF1 related Reactome pathways (count: 0)
PRF1 related interactors from protein-protein interaction data in HPRD (count: 3)