Gene Report

Basic Information

Approved Symbol	PPFIBP2
Approved Name	PTPRF interacting protein, binding protein 2 (liprin beta 2)
Symbol Alias	Cclp1
Location	11p15.4
Position	chr11:7534996-7674996 (+)
External Links	Entrez Gene: 8495 Ensembl: ENSG00000166387 UCSC: uc001mfj.4 HGNC ID: 9250
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between PPFIBP2 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
PPFIBP2	Aston, 2005	patients and normal controls		Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between PPFIBP2 and other components at different levels (count: 0)

Positive relationship network of PPFIBP2 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between PPFIBP2 and MDD (count: 0)

Negative relationships between PPFIBP2 and other components at different levels (count: 0)

PPFIBP2 related SNPs in MK4MDD (count: 0)

PPFIBP2 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Liprin-beta-2	Q8ND30	0(0/0)	Gene mapped

PPFIBP2 related GO terms (count: 5)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0005622	intracellular	cellular component	TAS[9624153]
GO:0007154	cell communication	biological process	NAS
GO:0003674	molecular_function	molecular function	ND
GO:0008907	integrase activity	molecular function	IEA
GO:0003677	DNA binding	molecular function	IEA

PPFIBP2 related KEGG pathways (count: 0)

PPFIBP2 related BioCarta pathways (count: 0)

PPFIBP2 related Reactome pathways (count: 0)

PPFIBP2 related interactors from protein-protein interaction data in HPRD (count: 6)

Gene	Interactor	Interactor in MK4MDD?	Experiment Type	PMID
PPFIBP2	TSG101	No	yeast 2-hybrid	16189514
PPFIBP2	PTPRC	No	in vitro	9624153
PPFIBP2	PPFIA3	No	in vitro	9624153
PPFIBP2	PPFIA2	No	in vitro	9624153
PPFIBP2	DTNB	No	yeast 2-hybrid	16189514
PPFIBP2	PPFIA1	No	in vitro;in vivo	9624153

Gene Report

Gene mapped GO terms