MK4MDD

Neurobiological Component Report

Basic Information
Name P3a
Description The P3a, or novelty P3, is a component of time-locked (EEG) signals known as event-related potentials (ERP). The P3a is a positive-going scalp-recorded brain potential that has a maximum amplitude over frontal/central electrode sites with a peak latency falling in the range of 250-280 ms.
No. of Studies (Positive/Negative) 3 (3/0) Help

Positive relationship between P3a and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
P3-1 Pause, 2003 patients and normal controls At the beginning of the therapy, visual stimulus processing ...... At the beginning of the therapy, visual stimulus processing was attenuated in depressive subjects at a relatively late processing level (reduced amplitudes of the P3 and pSW in response to colors and emotional slides), whereas olfactory stimulus processing had already been affected at an early level (reduced amplitudes of the P2 and P3-1 peaks in MDD patients). More...
late component of the P3a Lepisto, 2004 patients and normal controls The late component of the P3a (lP3a) was enhanced in amplitu...... The late component of the P3a (lP3a) was enhanced in amplitude in the patients as compared with that in the controls. More...
P300a Kohler, 2011 patients and normal controls P-value = 0.027 Patients further showed prolonged P300a latencies (p = 0.027...... Patients further showed prolonged P300a latencies (p = 0.027) More...

Positive relationships between P3a and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment

Positive relationship network of P3a in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between P3a and MDD (count: 0)
Negative relationships between P3a and other components at different levels (count: 0) Help