MK4MDD

Brain Morphology and Function Report

Basic Information
Name Nucleus accumbens
Brain Morphology The nucleus accumbens (NAcc) is a collection of neurons within the striatum.
Brain Function "It is thought to play an important role in reward, pleasure, laughter, addiction, aggression, fear, and the placebo effect."
Picture Nucleus accumbens From Wiki. Magnify
No. of Studies (Positive/Negative) 8(8/0) Help

Positive relationships between Nucleus accumbens and MDD (count: 4)
Name in Literature Reference Research Type Statistical Result Relation Description Help
nucleus accumbens Pizzagalli, 2009 patients and normal controls Relative to comparison subjects, participants with major dep...... Relative to comparison subjects, participants with major depression showed significantly weaker responses to gains in the left nucleus accumbens. More...
nucleus accumbens (NAcc) Heller AS, 2009 patients and normal controls While up-regulating positive affect, depressed individuals f...... While up-regulating positive affect, depressed individuals failed to sustain nucleus accumbens activity over time compared with controls. More...
nucleus accumbens Monk, 2008 high-risk people and normal controls When attention was unconstrained, high-risk subjects showed ...... When attention was unconstrained, high-risk subjects showed greater nucleus accumbens activation to fearful faces and lower nucleus accumbens activation to happy faces. More...
nucleus accumbens Hsu, 2010 patients and normal controls Negative correlations were also found in the nucleus accumbe...... Negative correlations were also found in the nucleus accumbens, which are implicated in the pathophysiology of MDD. More...

Positive relationships between Nucleus accumbens and other components at different levels (count: 5) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Nucleus accumbens in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Nucleus accumbens and MDD (count: 0)
Negative relationships between Nucleus accumbens and other components at different levels (count: 0) Help