Gene Report

Basic Information

Approved Symbol	NAA15
Approved Name	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Previous Symbol	NARG1
Previous Name	NMDA receptor regulated 1
Symbol Alias	TBDN100, NATH, FLJ13340
Location	4q31.1
Position	chr4:140222676-140311935 (+)
External Links	Entrez Gene: 80155 Ensembl: ENSG00000164134 UCSC: uc003ihu.1 HGNC ID: 30782
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between NAA15 and MDD (count: 0)

Positive relationships between NAA15 and other components at different levels (count: 1)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Name in Literature	Related Components
NMDA receptor		SETDB1(SETDB1)	gene	Jiang Y, 2010	animal model		In wild-type mice, systemic treatment with the NR2B antagoni...... In wild-type mice, systemic treatment with the NR2B antagonist, Ro25-6981 [R-(R,S)-alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine propranol], and hippocampal small interfering RNA-mediated NR2B/Grin2b(NMDA receptor subunit) knockdown resulted in behavioral changes similar to those elicited by the Setdb1 transgene. More...

Positive relationship network of NAA15 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between NAA15 and MDD (count: 0)

Negative relationships between NAA15 and other components at different levels (count: 0)

NAA15 related SNPs in MK4MDD (count: 0)

NAA15 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
N-alpha-acetyltransferase 15, NatA auxiliary subunit	Q9BXJ9	0(0/0)	Gene mapped

NAA15 related GO terms (count: 12)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0006474	N-terminal protein amino acid acetylation	biological process	IDA[15496142]
GO:0005737	cytoplasm	cellular component	IDA
GO:0001525	angiogenesis	biological process	IEA
GO:0006351	transcription, DNA-dependent	biological process	IEA
GO:0008080	N-acetyltransferase activity	molecular function	IEA
GO:0005667	transcription factor complex	cellular component	IDA[12145306]
GO:0043022	ribosome binding	molecular function	IDA[15496142]
GO:0030154	cell differentiation	biological process	IEA
GO:0045893	positive regulation of transcription, DNA-dependent	biological process	IDA[12145306]
GO:0005515	protein binding	molecular function	IPI[16507339]
GO:0016407	acetyltransferase activity	molecular function	IDA[15496142]
GO:0005634	nucleus	cellular component	IDA[12145306]

NAA15 related KEGG pathways (count: 0)

NAA15 related BioCarta pathways (count: 0)

NAA15 related Reactome pathways (count: 0)

NAA15 related interactors from protein-protein interaction data in HPRD (count: 5)

Gene	Interactor	Interactor in MK4MDD?	Experiment Type	PMID
NAA15	XRCC6	No	in vitro	12145309
NAA15	XRCC5	No	in vitro	12145312
NAA15	NAA11	No	in vivo	16638120
NAA15	NAA10	No	in vivo	19480662
NAA15	RPL26	No	in vivo	19480662

Gene Report

Gene mapped GO terms