MK4MDD

Molecule Report

Basic Information
Name Melatonin
Description A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
MeSH ID D008550
No. of Studies (Positive/Negative) 1(1/0) Help

Positive relationship between Melatonin and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
melatonin Buckley, 2010 patients and normal controls Phase angle (phase angle between cortisol acrophase and dim-...... Phase angle (phase angle between cortisol acrophase and dim-light melatonin onset) was significantly increased in MDD's versus healthy controls (13.40+/-1.61h. versus 11.61+/-1.66h, p=0.026). More...

Positive relationships between Melatonin and other components at different levels (count: 0) Help
Positive relationship network of Melatonin in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between Melatonin and MDD (count: 0)
Negative relationships between Melatonin and other components at different levels (count: 0) Help