Gene Report

Basic Information

Approved Symbol	MYRF
Approved Name	myelin regulatory factor
Previous Symbol	C11orf9
Previous Name	chromosome 11 open reading frame 9
Symbol Alias	Ndt80, pqn-47, MRF
Name Alias	myelin gene regulatory factor
Location	11q12-q13.1
Position	chr11:61520121-61555989 (+)
External Links	Entrez Gene: 745 Ensembl: ENSG00000124920 UCSC: uc001nsc.1 HGNC ID: 1181
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between MYRF and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
C11ORF9	Aston, 2005	patients and normal controls		Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between MYRF and other components at different levels (count: 0)

Positive relationship network of MYRF in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between MYRF and MDD (count: 0)

Negative relationships between MYRF and other components at different levels (count: 0)

MYRF related SNPs in MK4MDD (count: 0)

MYRF related proteins in MK4MDD (count: 0)

MYRF related GO terms (count: 11)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0031643	positive regulation of myelination	biological process	ISS
GO:0005634	nucleus	cellular component	ISS
GO:0003677	DNA binding	molecular function	IEA
GO:0032286	central nervous system myelin maintenance	biological process	ISS
GO:0022010	central nervous system myelination	biological process	ISS
GO:0014003	oligodendrocyte development	biological process	ISS
GO:0016021	integral to membrane	cellular component	IEA
GO:0006351	transcription, DNA-dependent	biological process	IEA
GO:0003700	sequence-specific DNA binding transcription factor activity	molecular function	IEA
GO:0048709	oligodendrocyte differentiation	biological process	ISS
GO:0045893	positive regulation of transcription, DNA-dependent	biological process	ISS

MYRF related KEGG pathways (count: 0)

MYRF related BioCarta pathways (count: 0)

MYRF related Reactome pathways (count: 0)

MYRF related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms