MK4MDD

Gene Report

Basic Information
Approved Symbol MAP4K4
Approved Name mitogen-activated protein kinase kinase kinase kinase 4
Symbol Alias HGK, NIK, FLH21957
Name Alias "HPK/GCK-like kinase", "hepatocyte progenitor kinase-like/germinal center kinase-like kinase"
Location 2q11.2-q12
Position chr2:102507712-102508475 (+)
External Links Entrez Gene: 9448
Ensembl: ENSG00000071054
UCSC: uc002tbf.3
HGNC ID: 6866
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between MAP4K4 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
MAP4K4 Jansen R, 2015 patients and normal controls P-value=0.000176;FDR=0.0918;beta=0.225 we found 129 genes (142 probesets) differentially expressed ...... we found 129 genes (142 probesets) differentially expressed between the control and current MDD groups (FDR<0.1) More...

Positive relationships between MAP4K4 and other components at different levels (count: 0) Help
Positive relationship network of MAP4K4 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between MAP4K4 and MDD (count: 0)
Negative relationships between MAP4K4 and other components at different levels (count: 0) Help
MAP4K4 related SNPs in MK4MDD (count: 0)
MAP4K4 related proteins in MK4MDD (count: 0)
MAP4K4 related GO terms (count: 22)
MAP4K4 related KEGG pathways (count: 1)
MAP4K4 related BioCarta pathways (count: 1)
MAP4K4 related Reactome pathways (count: 0)
MAP4K4 related interactors from protein-protein interaction data in HPRD (count: 9)